Metabolic Testing Validation:
PNOĒ’s Clinically Proven Accuracy
PNOĒ delivers clinical-grade metabolic testing through a validated metabolic testing device trusted by healthcare providers, fitness professionals, and researchers worldwide. Backed by peer-reviewed studies, PNOĒ offers scientifically proven metabolic testing outside the lab — helping you personalize care, optimize performance, and improve long-term health outcomes using breath-based metrics.
Lab Validation:
Accuracy You Can Trust
In a tightly controlled breath analysis validation study, researchers compared the PNOĒ portable metabolic analyzer to the gold-standard COSMED Quark CPET system. Results showed near-perfect agreement across all major metrics: VO2, VCO2, RQ, and ventilation. PNOĒ achieved correlation coefficients of r ≈ 0.98 and test-retest reliability around ICC ≈ 0.98 — confirming its clinical precision.
This level of metabolic testing validation makes PNOĒ the first portable system to rival lab-grade analyzers from rest to max exertion.
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This level of metabolic testing validation makes PNOĒ the first portable system to rival lab-grade analyzers from rest to max exertion.
Read more
In a tightly controlled breath analysis validation study, researchers compared the PNOĒ portable metabolic analyzer to the gold-standard COSMED Quark CPET system. Results showed near-perfect agreement across all major metrics: VO2, VCO2, RQ, and ventilation. PNOĒ achieved correlation coefficients of r ≈ 0.98 and test-retest reliability around ICC ≈ 0.98 — confirming its clinical precision.
This level of metabolic testing validation makes PNOĒ the first portable system to rival lab-grade analyzers from rest to max exertion.
PNOĒ’s clinical value was demonstrated in a study involving cancer patients on JAK inhibitors. Researchers tracked resting metabolic rate (RMR) using PNOĒ and identified unique shifts in energy expenditure linked to treatment phases. These findings helped explain unintended weight changes—insights not available through bloodwork alone.
This study contributes to the growing body of metabolic testing validation confirming PNOĒ’s clinical accuracy. By enabling point-of-care breath analysis validation, PNOĒ opens a new frontier in treatment monitoring.
Learn more
This study contributes to the growing body of metabolic testing validation confirming PNOĒ’s clinical accuracy. By enabling point-of-care breath analysis validation, PNOĒ opens a new frontier in treatment monitoring.
Learn more
Clinical Use: Applying Metabolic Testing in Medical Settings
PNOĒ’s clinical value was demonstrated in a study involving cancer patients on JAK inhibitors. Researchers tracked resting metabolic rate (RMR) using PNOĒ and identified unique shifts in energy expenditure linked to treatment phases. These findings helped explain unintended weight changes—insights not available through bloodwork alone.
This study contributes to the growing body of metabolic testing validation confirming PNOĒ’s clinical accuracy. By enabling point-of-care breath analysis validation, PNOĒ opens a new frontier in treatment monitoring.
Learn more
This study contributes to the growing body of metabolic testing validation confirming PNOĒ’s clinical accuracy. By enabling point-of-care breath analysis validation, PNOĒ opens a new frontier in treatment monitoring.
Learn more
Fitness Testing: Real-Time Performance in Dynamic Settings
In a high-intensity functional training (HIFT) study, PNOĒ tracked every breath across a 35-minute session. Participants burned ~528 kcal, peaked at 172 bpm, and hit a MET score of 12.2 — proving that PNOĒ can capture real-time demands in active workouts, not just labs.
This data validates the use of PNOĒ in dynamic, group-based fitness — turning real-world workouts into quantifiable metabolic insights.
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This data validates the use of PNOĒ in dynamic, group-based fitness — turning real-world workouts into quantifiable metabolic insights.
Read more
In a high-intensity functional training (HIFT) study, PNOĒ tracked every breath across a 35-minute session. Participants burned ~528 kcal, peaked at 172 bpm, and hit a MET score of 12.2 — proving that PNOĒ can capture real-time demands in active workouts, not just labs.
This data validates the use of PNOĒ in dynamic, group-based fitness — turning real-world workouts into quantifiable metabolic insights.
Read more
This data validates the use of PNOĒ in dynamic, group-based fitness — turning real-world workouts into quantifiable metabolic insights.
Read more
PNOĒ’s versatility was proven in a study on electric skateboarding, revealing an average burn of 12.5 kcal/min and MET score of 10.5 — higher than snowboarding. Quad activation hit 140% MVC during turns, confirming intense muscular demand.
This research confirms the metabolic testing validation of PNOĒ across unconventional and emerging sports.
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This research confirms the metabolic testing validation of PNOĒ across unconventional and emerging sports.
Learn more
Breath Testing Beyond
the Gym
PNOĒ’s versatility was proven in a study on electric skateboarding, revealing an average burn of 12.5 kcal/min and MET score of 10.5 — higher than snowboarding. Quad activation hit 140% MVC during turns, confirming intense muscular demand.
This research confirms the metabolic testing validation of PNOĒ across unconventional and emerging sports.
Learn more
This research confirms the metabolic testing validation of PNOĒ across unconventional and emerging sports.
Learn more
Threshold Testing in Elite Endurance Sports
PNOĒ was used to cross-validate Stryd’s 9/3-minute field test with lab-grade VO2 Max data in elite runners. Results showed the critical power threshold aligned with the respiratory compensation point (~89% of VO₂max), affirming the use of breath-based thresholds in performance coaching.
This level of validated metabolic testing helps athletes and coaches fine-tune training prescriptions with unmatched precision.
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This level of validated metabolic testing helps athletes and coaches fine-tune training prescriptions with unmatched precision.
Learn more
PNOĒ was used to cross-validate Stryd’s 9/3-minute field test with lab-grade VO2 Max data in elite runners. Results showed the critical power threshold aligned with the respiratory compensation point (~89% of VO₂max), affirming the use of breath-based thresholds in performance coaching.
This level of validated metabolic testing helps athletes and coaches fine-tune training prescriptions with unmatched precision.
Learn more
This level of validated metabolic testing helps athletes and coaches fine-tune training prescriptions with unmatched precision.
Learn more
In 2025, researchers built a two-phase gas exchange model using PNOĒ data from overweight cyclists. The model predicted O2 and CO2 exchange with 84–89% accuracy, enabling real-time adjustments to training intensity.
It marks a move from static programming to responsive, data-driven training powered by PNOĒ’s breath analysis, backed by independent metabolic testing validation
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It marks a move from static programming to responsive, data-driven training powered by PNOĒ’s breath analysis, backed by independent metabolic testing validation
Learn more
Smart Coaching:
Adaptive Training via Gas Exchange Modeling
In 2025, researchers built a two-phase gas exchange model using PNOĒ data from overweight cyclists. The model predicted O2 and CO2 exchange with 84–89% accuracy, enabling real-time adjustments to training intensity.
It marks a move from static programming to responsive, data-driven training powered by PNOĒ’s breath analysis, backed by independent metabolic testing validation
Learn more
It marks a move from static programming to responsive, data-driven training powered by PNOĒ’s breath analysis, backed by independent metabolic testing validation
Learn more
Home & Clinic Monitoring: Metabolic Health for Everyone
Today, PNOĒ offers scientific validation of key health biomarkers such as VO2 Max, resting metabolic rate (RMR), fat and carbohydrate usage, and biological age – all through a simple breath test. Its clinically proven system empowers individuals to monitor their metabolic profile from anywhere: home, clinic, or gym.
With this validated metabolic testing device, anyone can gain insight into aging, disease risk, and performance – making PNOĒ’s role in metabolic testing validation essential to personalizing health with confidence.
Explore breath analysis
With this validated metabolic testing device, anyone can gain insight into aging, disease risk, and performance – making PNOĒ’s role in metabolic testing validation essential to personalizing health with confidence.
Explore breath analysis
Today, PNOĒ offers scientific validation of key health biomarkers such as VO2 Max, resting metabolic rate (RMR), fat and carbohydrate usage, and biological age – all through a simple breath test. Its clinically proven system empowers individuals to monitor their metabolic profile from anywhere: home, clinic, or gym.
With this validated metabolic testing device, anyone can gain insight into aging, disease risk, and performance – making PNOĒ’s role in metabolic testing validation essential to personalizing health with confidence.
Explore breath analysis
With this validated metabolic testing device, anyone can gain insight into aging, disease risk, and performance – making PNOĒ’s role in metabolic testing validation essential to personalizing health with confidence.
Explore breath analysis
