Clinical-grade metabolic testing is central to Dr. Leonard Pastrana’s approach to peptide therapy and longevity medicine. At NuBioAge, he uses PNOĒ’s metabolic breath analysis to guide interventions in cellular medicine and optimize patient outcomes.
Dr. Pastrana, a clinical pharmacist and expert in peptide-based protocols, leads one of the country’s most innovative clinics in metabolic health. His model centers on preventative diagnostics, cellular efficiency, and data-driven personalization. To achieve this, he needed a tool that could quantify systemic metabolic function in real time — not just based on labs or symptoms. Through clinical-grade metabolic testing, patients can gain a full view of how peptide protocols affect systemic health over time.
In functional and longevity medicine, validating treatment efficacy remains a challenge. Many interventions — including peptide therapy, hormone replacement, and pharmacological solutions — rely on blood biomarkers and subjective symptom tracking. This challenge underscores the importance of clinical-grade metabolic testing as a standard of care in functional protocols.
However, these methods often lack real-time insights into metabolic efficiency, energy utilization, and mitochondrial performance. Dr. Pastrana sought a precise, non-invasive, and clinically relevant tool to measure:
PNOĒ’s breath analysis delivers real-time metabolic data, allowing Dr. Pastrana to customize interventions based on oxygen consumption, fat oxidation, and mitochondrial function. By tracking 23 key biomarkers — including VO2 Max, resting metabolic rate (RMR), and respiratory exchange ratio (RER) — PNOĒ supports precise, personalized protocols. Clinical-grade metabolic testing offered by PNOĒ ensures each treatment decision is informed by real-time data.
In his peptide therapy programs, PNOĒ plays a vital role in:
A 40-year-old male patient with long COVID reported:
Intervention:
Outcome:
Using clinical-grade metabolic testing, Dr. Pastrana validated mitochondrial performance recovery in this case.
Beyond clinical use, Dr. Pastrana also leverages PNOĒ to educate patients. Many individuals undergoing peptide therapy struggle to understand how cellular-level changes translate to daily energy, fat burn, or exercise tolerance. PNOĒ’s reports and visualizations offer a patient-friendly way to track VO2 Max improvements, monitor metabolic flexibility, and connect biomarker shifts with lifestyle changes. This not only enhances compliance but builds confidence in the care plan.
With each follow-up, the breath analysis serves as a checkpoint, helping identify when to intensify a protocol, maintain it, or introduce new interventions. For example, when a patient’s fat oxidation improves but recovery scores decline, Dr. Pastrana may adjust peptide timing, modify training zones, or integrate supportive supplements. This iterative, evidence-based model enhances outcomes and avoids the one-size-fits-all trap common in regenerative care.
Offering clinical-grade metabolic testing helped NuBioAge stand out in a crowded longevity market.
By integrating clinical-grade metabolic testing through PNOĒ, Dr. Pastrana bridges the gap between pharmaceutical science and functional medicine. Whether optimizing recovery, performance, or metabolic health, breath analysis offers the clarity needed to deliver precision care, improve outcomes, and lead in the evolving landscape of longevity medicine.
What type of health business are you running?